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HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon

Innate immune sensing of viral infection results in type I interferon (IFN) production and inflammasome activation. Type I IFNs, primarily IFN-α and IFN-β, are produced by all cell types upon virus infection and promote an antiviral state in surrounding cells by inducing the expression of IFN-stimul...

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Detalles Bibliográficos
Autores principales:	Chattergoon, Michael A., Latanich, Rachel, Quinn, Jeffrey, Winter, Matthew E., Buckheit, Robert W., Blankson, Joel N., Pardoll, Drew, Cox, Andrea L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006909/ https://www.ncbi.nlm.nih.gov/pubmed/24788318 http://dx.doi.org/10.1371/journal.ppat.1004082

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