Epigenetic control of mobile DNA as an interface between experience and genome change

Mobile DNA in the genome is subject to RNA-targeted epigenetic control. This control regulates the activity of transposons, retrotransposons and genomic proviruses. Many different life history experiences alter the activities of mobile DNA and the expression of genetic loci regulated by nearby inser...

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Detalles Bibliográficos
Autor principal: Shapiro, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007016/
https://www.ncbi.nlm.nih.gov/pubmed/24795749
http://dx.doi.org/10.3389/fgene.2014.00087
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author Shapiro, James A.
author_facet Shapiro, James A.
author_sort Shapiro, James A.
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description Mobile DNA in the genome is subject to RNA-targeted epigenetic control. This control regulates the activity of transposons, retrotransposons and genomic proviruses. Many different life history experiences alter the activities of mobile DNA and the expression of genetic loci regulated by nearby insertions. The same experiences induce alterations in epigenetic formatting and lead to trans-generational modifications of genome expression and stability. These observations lead to the hypothesis that epigenetic formatting directed by non-coding RNA provides a molecular interface between life history events and genome alteration.
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spelling pubmed-40070162014-05-02 Epigenetic control of mobile DNA as an interface between experience and genome change Shapiro, James A. Front Genet Genetics Mobile DNA in the genome is subject to RNA-targeted epigenetic control. This control regulates the activity of transposons, retrotransposons and genomic proviruses. Many different life history experiences alter the activities of mobile DNA and the expression of genetic loci regulated by nearby insertions. The same experiences induce alterations in epigenetic formatting and lead to trans-generational modifications of genome expression and stability. These observations lead to the hypothesis that epigenetic formatting directed by non-coding RNA provides a molecular interface between life history events and genome alteration. Frontiers Media S.A. 2014-04-25 /pmc/articles/PMC4007016/ /pubmed/24795749 http://dx.doi.org/10.3389/fgene.2014.00087 Text en Copyright © 2014 Shapiro. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Shapiro, James A.
Epigenetic control of mobile DNA as an interface between experience and genome change
title Epigenetic control of mobile DNA as an interface between experience and genome change
title_full Epigenetic control of mobile DNA as an interface between experience and genome change
title_fullStr Epigenetic control of mobile DNA as an interface between experience and genome change
title_full_unstemmed Epigenetic control of mobile DNA as an interface between experience and genome change
title_short Epigenetic control of mobile DNA as an interface between experience and genome change
title_sort epigenetic control of mobile dna as an interface between experience and genome change
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007016/
https://www.ncbi.nlm.nih.gov/pubmed/24795749
http://dx.doi.org/10.3389/fgene.2014.00087
work_keys_str_mv AT shapirojamesa epigeneticcontrolofmobilednaasaninterfacebetweenexperienceandgenomechange

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