Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α(1)-antitrypsin

Overexpression of Z α(1)-antitrypsin is known to induce polymer formation, prime the cells for endoplasmic reticulum stress and initiate nuclear factor kappa B (NF-κB) signalling. However, whether endogenous expression in primary bronchial epithelial cells has similar consequences remains unclear. M...

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Detalles Bibliográficos
Autores principales: van ‘t Wout, Emily F.A., Dickens, Jennifer A., van Schadewijk, Annemarie, Haq, Imran, Kwok, Hang Fai, Ordóñez, Adriana, Murphy, Gillian, Stolk, Jan, Lomas, David A., Hiemstra, Pieter S., Marciniak, Stefan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007119/
https://www.ncbi.nlm.nih.gov/pubmed/24097797
http://dx.doi.org/10.1093/hmg/ddt487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007119/
https://www.ncbi.nlm.nih.gov/pubmed/24097797
http://dx.doi.org/10.1093/hmg/ddt487

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