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RUNX family members are covalently modified and regulated by PIAS1-mediated sumoylation
Transcription factors of the RUNX family (RUNXs), which play pivotal roles in normal development and neoplasia, are regulated by various post-translational modifications. To understand the molecular mechanisms underlying the regulation of RUNXs, we performed a large-scale functional genetic screen o...
Autores principales: | Kim, J-H, Jang, J-W, Lee, Y-S, Lee, J-W, Chi, X-Z, Li, Y-H, Kim, M-K, Kim, D-M, Choi, B-S, Kim, J, Kim, H-M, van Wijnen, A, Park, IlY, Bae, S-C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007197/ https://www.ncbi.nlm.nih.gov/pubmed/24777122 http://dx.doi.org/10.1038/oncsis.2014.15 |
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