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Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis

The synthetic cannabinoid WIN 55,212-2 is a potent cannabinoid receptor agonist with anticancer potential. Experiments were performed to determine the effects of WIN on proliferation, cell cycle distribution, and programmed cell death in human osteosarcoma MG63 and Saos-2 cells. Results show that WI...

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Detalles Bibliográficos
Autores principales: Notaro, Antonietta, Sabella, Selenia, Pellerito, Ornella, Di Fiore, Riccardo, De Blasio, Anna, Vento, Renza, Calvaruso, Giuseppe, Giuliano, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007360/
https://www.ncbi.nlm.nih.gov/pubmed/24795528
http://dx.doi.org/10.7150/ijbs.8337