Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann

The Bohmann lab, based at the University of Rochester Medical Center in New York, uses Drosophila to explore the cross-talk between stress and metabolic regulation, with the goal of understanding how the signaling pathways involved can drive aging, cancer and other degenerative pathologies. In this...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
A Model For Life
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007401/
https://www.ncbi.nlm.nih.gov/pubmed/24795432
http://dx.doi.org/10.1242/dmm.016329
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description The Bohmann lab, based at the University of Rochester Medical Center in New York, uses Drosophila to explore the cross-talk between stress and metabolic regulation, with the goal of understanding how the signaling pathways involved can drive aging, cancer and other degenerative pathologies. In this interview, Dirk Bohmann describes his motives for moving into the fly field, explains how the study of aging can give important insights into complex disease mechanisms, and advocates using a systems-biology approach to advance drug discovery.
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spelling pubmed-40074012014-05-14 Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann Dis Model Mech A Model For Life The Bohmann lab, based at the University of Rochester Medical Center in New York, uses Drosophila to explore the cross-talk between stress and metabolic regulation, with the goal of understanding how the signaling pathways involved can drive aging, cancer and other degenerative pathologies. In this interview, Dirk Bohmann describes his motives for moving into the fly field, explains how the study of aging can give important insights into complex disease mechanisms, and advocates using a systems-biology approach to advance drug discovery. The Company of Biologists Limited 2014-05 /pmc/articles/PMC4007401/ /pubmed/24795432 http://dx.doi.org/10.1242/dmm.016329 Text en © 2014. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle A Model For Life
Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann
title Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann
title_full Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann
title_fullStr Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann
title_full_unstemmed Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann
title_short Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann
title_sort towards a systems-level understanding of aging and cancer: an interview with dirk bohmann
topic A Model For Life
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007401/
https://www.ncbi.nlm.nih.gov/pubmed/24795432
http://dx.doi.org/10.1242/dmm.016329

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