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Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicity
α-synuclein (aSyn) expression is implicated in neurodegenerative processes, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). In animal models of these diseases, axon pathology often precedes cell death, raising the question of whether aSyn has compartment-specific toxic effect...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007408/ https://www.ncbi.nlm.nih.gov/pubmed/24626988 http://dx.doi.org/10.1242/dmm.013185 |