SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells

BACKGROUND: SMAD4 is a gastrointestinal malignancy-specific tumor suppressor gene found mutated in one third of colorectal cancer specimens and half of pancreatic tumors. SMAD4 inactivation by allelic deletion or intragenic mutation mainly occurs in the late stage of human pancreatic ductal adenocar...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yu-Wen, Hsiao, Pi-Jung, Weng, Ching-Chieh, Kuo, Kung-Kai, Kuo, Tzu-Lei, Wu, Deng-Chyang, Hung, Wen-Chun, Cheng, Kuang-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007528/
https://www.ncbi.nlm.nih.gov/pubmed/24625091
http://dx.doi.org/10.1186/1471-2407-14-181

Ejemplares similares

Ejemplares similares