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Evolution of Bacterial Protein-Tyrosine Kinases and Their Relaxed Specificity Toward Substrates
It has often been speculated that bacterial protein-tyrosine kinases (BY-kinases) evolve rapidly and maintain relaxed substrate specificity to quickly adopt new substrates when evolutionary pressure in that direction arises. Here, we report a phylogenomic and biochemical analysis of BY-kinases, and...
Autores principales: | Shi, Lei, Ji, Boyang, Kolar-Znika, Lorena, Boskovic, Ana, Jadeau, Fanny, Combet, Christophe, Grangeasse, Christophe, Franjevic, Damjan, Talla, Emmanuel, Mijakovic, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007543/ https://www.ncbi.nlm.nih.gov/pubmed/24728941 http://dx.doi.org/10.1093/gbe/evu056 |
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