A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome

BACKGROUND: To evaluate the safety of combination vaccine treatment of multiple peptides, phase I clinical trial was conducted for patients with advanced colorectal cancer using five novel HLA-A*2402-restricted peptides, three peptides derived from oncoantigens, ring finger protein 43 (RNF43), 34 kD...

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Detalles Bibliográficos
Autores principales: Hazama, Shoichi, Nakamura, Yusuke, Takenouchi, Hiroko, Suzuki, Nobuaki, Tsunedomi, Ryouichi, Inoue, Yuka, Tokuhisa, Yoshihiro, Iizuka, Norio, Yoshino, Shigefumi, Takeda, Kazuyoshi, Shinozaki, Hirokazu, Kamiya, Akira, Furukawa, Hiroyuki, Oka, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007571/
https://www.ncbi.nlm.nih.gov/pubmed/24612787
http://dx.doi.org/10.1186/1479-5876-12-63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007571/
https://www.ncbi.nlm.nih.gov/pubmed/24612787
http://dx.doi.org/10.1186/1479-5876-12-63

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