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Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin
BACKGROUND: The bacterial ribosome is a primary target of several classes of antibiotics. Investigation of the structure of the ribosomal subunits in complex with different antibiotics can reveal the mode of inhibition of ribosomal protein synthesis. Analysis of the interactions between antibiotics...
Autores principales: | Harms, Jörg M, Schlünzen, Frank, Fucini, Paola, Bartels, Heike, Yonath, Ada |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400760/ https://www.ncbi.nlm.nih.gov/pubmed/15059283 http://dx.doi.org/10.1186/1741-7007-2-4 |
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