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Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA
BACKGROUND: The accumulation of misfolded proteins appears as a fundamental pathogenic process in human neurodegenerative diseases. In the case of synucleinopathies such as Parkinson’s disease (PD) or dementia with Lewy bodies (DLB), the intraneuronal deposition of aggregated alpha-synuclein (αS) is...
Autores principales: | Bétemps, Dominique, Verchère, Jérémy, Brot, Sébastien, Morignat, Eric, Bousset, Luc, Gaillard, Damien, Lakhdar, Latifa, Melki, Ronald, Baron, Thierry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007641/ https://www.ncbi.nlm.nih.gov/pubmed/24624994 http://dx.doi.org/10.1186/2051-5960-2-29 |
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