Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings

BACKGROUND: Tumor endothelial transdifferentiation and VEGFR1/2 expression by cancer cells have been reported in glioblastoma but remain poorly documented for many other cancer types. METHODS: To characterize vasculature of patient-derived tumor xenografts (PDXs), largely used in preclinical anti-an...

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Detalles Bibliográficos
Autores principales: Bieche, Ivan, Vacher, Sophie, Vallerand, David, Richon, Sophie, Hatem, Rana, De Plater, Ludmilla, Dahmani, Ahmed, Némati, Fariba, Angevin, Eric, Marangoni, Elisabetta, Roman-Roman, Sergio, Decaudin, Didier, Dangles-Marie, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007753/
https://www.ncbi.nlm.nih.gov/pubmed/24625025
http://dx.doi.org/10.1186/1471-2407-14-178

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