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Characterization of Calmodulin–Fas Death Domain Interaction: An Integrated Experimental and Computational Study
[Image: see text] The Fas death receptor-activated death-inducing signaling complex (DISC) regulates apoptosis in many normal and cancer cells. Qualitative biochemical experiments demonstrate that calmodulin (CaM) binds to the death domain of Fas. The interaction between CaM and Fas regulates Fas-me...
Autores principales: | Fancy, Romone M., Wang, Lingyun, Napier, Tiara, Lin, Jiabei, Jing, Gu, Lucius, Aaron L., McDonald, Jay M., Zhou, Tong, Song, Yuhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007977/ https://www.ncbi.nlm.nih.gov/pubmed/24702583 http://dx.doi.org/10.1021/bi500228h |
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