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Molecular Dynamics of the Proline Switch and Its Role in Crk Signaling
[Image: see text] The Crk adaptor proteins play a central role as a molecular timer for the formation of protein complexes including various growth and differentiation factors. The loss of regulation of Crk results in many kinds of cancers. A self-regulatory mechanism for Crk was recently proposed,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007982/ https://www.ncbi.nlm.nih.gov/pubmed/24702481 http://dx.doi.org/10.1021/jp5013297 |