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Biologic therapy for psoriasis - still searching for the best target()

Psoriasis is a chronic skin disease that results from the complex interaction between genetic and environmental factors. Over the last few decades, scientific evidence has redirected the focus of therapeutic studies to the immunologic pathways underlying its pathogenesis. This led to the biologic bo...

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Detalles Bibliográficos
Autores principales: Pinto-Almeida, Teresa, Torres, Tiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008081/
https://www.ncbi.nlm.nih.gov/pubmed/24770527
http://dx.doi.org/10.1590/abd1806-4841.20142898
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author Pinto-Almeida, Teresa
Torres, Tiago
author_facet Pinto-Almeida, Teresa
Torres, Tiago
author_sort Pinto-Almeida, Teresa
collection PubMed
description Psoriasis is a chronic skin disease that results from the complex interaction between genetic and environmental factors. Over the last few decades, scientific evidence has redirected the focus of therapeutic studies to the immunologic pathways underlying its pathogenesis. This led to the biologic boom that we are currently experiencing, with the development and approval of targeted progressively more selective biological therapies and ongoing clinical trials of increasingly specific drugs, given their important implications for long-term efficacy and safety. Nevertheless, the search for the optimal biologic is still ongoing, and the best target has yet to be found.
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spelling pubmed-40080812014-05-07 Biologic therapy for psoriasis - still searching for the best target() Pinto-Almeida, Teresa Torres, Tiago An Bras Dermatol Communication Psoriasis is a chronic skin disease that results from the complex interaction between genetic and environmental factors. Over the last few decades, scientific evidence has redirected the focus of therapeutic studies to the immunologic pathways underlying its pathogenesis. This led to the biologic boom that we are currently experiencing, with the development and approval of targeted progressively more selective biological therapies and ongoing clinical trials of increasingly specific drugs, given their important implications for long-term efficacy and safety. Nevertheless, the search for the optimal biologic is still ongoing, and the best target has yet to be found. Sociedade Brasileira de Dermatologia 2014 /pmc/articles/PMC4008081/ /pubmed/24770527 http://dx.doi.org/10.1590/abd1806-4841.20142898 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communication
Pinto-Almeida, Teresa
Torres, Tiago
Biologic therapy for psoriasis - still searching for the best target()
title Biologic therapy for psoriasis - still searching for the best target()
title_full Biologic therapy for psoriasis - still searching for the best target()
title_fullStr Biologic therapy for psoriasis - still searching for the best target()
title_full_unstemmed Biologic therapy for psoriasis - still searching for the best target()
title_short Biologic therapy for psoriasis - still searching for the best target()
title_sort biologic therapy for psoriasis - still searching for the best target()
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008081/
https://www.ncbi.nlm.nih.gov/pubmed/24770527
http://dx.doi.org/10.1590/abd1806-4841.20142898
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