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Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy

Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estr...

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Detalles Bibliográficos
Autores principales: Pan, Alexander L., Fergusson, David, Hong, Robert, Badawi, Ramy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008130/
https://www.ncbi.nlm.nih.gov/pubmed/24826258
http://dx.doi.org/10.1155/2012/524508
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author Pan, Alexander L.
Fergusson, David
Hong, Robert
Badawi, Ramy A.
author_facet Pan, Alexander L.
Fergusson, David
Hong, Robert
Badawi, Ramy A.
author_sort Pan, Alexander L.
collection PubMed
description Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized.
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spelling pubmed-40081302014-05-13 Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy Pan, Alexander L. Fergusson, David Hong, Robert Badawi, Ramy A. Case Rep Cardiol Case Report Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized. Hindawi Publishing Corporation 2012 2012-08-15 /pmc/articles/PMC4008130/ /pubmed/24826258 http://dx.doi.org/10.1155/2012/524508 Text en Copyright © 2012 Alexander L. Pan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Pan, Alexander L.
Fergusson, David
Hong, Robert
Badawi, Ramy A.
Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
title Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
title_full Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
title_fullStr Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
title_full_unstemmed Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
title_short Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
title_sort spontaneous coronary artery dissection following topical hormone replacement therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008130/
https://www.ncbi.nlm.nih.gov/pubmed/24826258
http://dx.doi.org/10.1155/2012/524508
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