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Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008130/ https://www.ncbi.nlm.nih.gov/pubmed/24826258 http://dx.doi.org/10.1155/2012/524508 |
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author | Pan, Alexander L. Fergusson, David Hong, Robert Badawi, Ramy A. |
author_facet | Pan, Alexander L. Fergusson, David Hong, Robert Badawi, Ramy A. |
author_sort | Pan, Alexander L. |
collection | PubMed |
description | Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized. |
format | Online Article Text |
id | pubmed-4008130 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-40081302014-05-13 Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy Pan, Alexander L. Fergusson, David Hong, Robert Badawi, Ramy A. Case Rep Cardiol Case Report Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized. Hindawi Publishing Corporation 2012 2012-08-15 /pmc/articles/PMC4008130/ /pubmed/24826258 http://dx.doi.org/10.1155/2012/524508 Text en Copyright © 2012 Alexander L. Pan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Pan, Alexander L. Fergusson, David Hong, Robert Badawi, Ramy A. Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_full | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_fullStr | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_full_unstemmed | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_short | Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy |
title_sort | spontaneous coronary artery dissection following topical hormone replacement therapy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008130/ https://www.ncbi.nlm.nih.gov/pubmed/24826258 http://dx.doi.org/10.1155/2012/524508 |
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