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Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine cover

BACKGROUND: An effective malaria vaccine remains elusive. The most effective experimental vaccines confer only limited and short-lived protection despite production of protective antibodies. However, immunization with irradiated sporozoites, or with live sporozoites under chloroquine cover, has resu...

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Detalles Bibliográficos
Autores principales: Brando, Clara, Richardson, Jason H, Murphy, Jittawadee, Ockenhouse, Christian F, Kamau, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008132/
https://www.ncbi.nlm.nih.gov/pubmed/24620841
http://dx.doi.org/10.1186/1475-2875-13-92