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Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor specimens

BACKGROUND: NanoString’s Prosigna™ Breast Cancer Prognostic Gene Signature Assay is based on the PAM50 gene expression signature. The test outputs a risk of recurrence (ROR) score, risk category, and intrinsic subtype (Luminal A/B, HER2-enriched, Basal-like). The studies described here were designed...

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Detalles Bibliográficos
Autores principales:	Nielsen, Torsten, Wallden, Brett, Schaper, Carl, Ferree, Sean, Liu, Shuzhen, Gao, Dongxia, Barry, Garrett, Dowidar, Naeem, Maysuria, Malini, Storhoff, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008304/ https://www.ncbi.nlm.nih.gov/pubmed/24625003 http://dx.doi.org/10.1186/1471-2407-14-177

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