In Vitro Evaluation of a Soluble Leishmania Promastigote Surface Antigen as a Potential Vaccine Candidate against Human Leishmaniasis

PSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in several Leishmania (L.) species. PSA is recognized by human Th1 cells and provides a high degree of protection in vaccinated mice. We evaluated humoral and cellular immune responses induced by a...

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Detalles Bibliográficos
Autores principales: Chamakh-Ayari, Rym, Bras-Gonçalves, Rachel, Bahi-Jaber, Narges, Petitdidier, Elodie, Markikou-Ouni, Wafa, Aoun, Karim, Moreno, Javier, Carrillo, Eugenia, Salotra, Poonam, Kaushal, Himanshu, Negi, Narender Singh, Arevalo, Jorge, Falconi-Agapito, Francesca, Privat, Angela, Cruz, Maria, Pagniez, Julie, Papierok, Gérard-Marie, Rhouma, Faten Bel Haj, Torres, Pilar, Lemesre, Jean-Loup, Chenik, Mehdi, Meddeb-Garnaoui, Amel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008367/
https://www.ncbi.nlm.nih.gov/pubmed/24786587
http://dx.doi.org/10.1371/journal.pone.0092708

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