Cargando…
Bioenergetics and Gene Silencing Approaches for Unraveling Nucleotide Recognition by the Human EIF2C2/Ago2 PAZ Domain
Gene silencing and RNA interference are major cellular processes that control gene expression via the cleavage of target mRNA. Eukaryotic translation initiation factor 2C2 (EIF2C2, Argonaute protein 2, Ago2) is considered to be the major player of RNAi as it is the core component of RISC complexes....
Autores principales: | Kandeel, Mahmoud, Al-Taher, Abdullah, Nakashima, Remi, Sakaguchi, Tomoya, Kandeel, Ali, Nagaya, Yuki, Kitamura, Yoshiaki, Kitade, Yukio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008379/ https://www.ncbi.nlm.nih.gov/pubmed/24788663 http://dx.doi.org/10.1371/journal.pone.0094538 |
Ejemplares similares
-
Computational Analysis of siRNA Recognition by the Ago2 PAZ Domain and Identification of the Determinants of RNA-Induced Gene Silencing
por: Kandeel, Mahmoud, et al.
Publicado: (2013) -
Repurposing FDA-approved phytomedicines, natural products, antivirals and cell protectives against SARS-CoV-2 (COVID-19) RNA-dependent RNA polymerase
por: Kandeel, Mahmoud, et al.
Publicado: (2020) -
The structural basis of unique substrate recognition by Plasmodium thymidylate kinase: Molecular dynamics simulation and inhibitory studies
por: Kandeel, Mahmoud, et al.
Publicado: (2019) -
Antiviral drug discovery by targeting the SARS-CoV-2 polyprotein processing by inhibition of the main protease
por: Kandeel, Mahmoud, et al.
Publicado: (2022) -
The Binding Interactions of the Macrolide Endectocide Ivermectin with the Antibiotics Ampicillin, Chloramphenicol and Tetracycline HCL
por: Kandeel, M., et al.
Publicado: (2012)