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Bioenergetics and Gene Silencing Approaches for Unraveling Nucleotide Recognition by the Human EIF2C2/Ago2 PAZ Domain

Gene silencing and RNA interference are major cellular processes that control gene expression via the cleavage of target mRNA. Eukaryotic translation initiation factor 2C2 (EIF2C2, Argonaute protein 2, Ago2) is considered to be the major player of RNAi as it is the core component of RISC complexes....

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Detalles Bibliográficos
Autores principales: Kandeel, Mahmoud, Al-Taher, Abdullah, Nakashima, Remi, Sakaguchi, Tomoya, Kandeel, Ali, Nagaya, Yuki, Kitamura, Yoshiaki, Kitade, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008379/
https://www.ncbi.nlm.nih.gov/pubmed/24788663
http://dx.doi.org/10.1371/journal.pone.0094538

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