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Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors

BACKGROUND: Small membrane-permeable molecules are now widely used during maintenance and differentiation of embryonic stem cells of different species. In particular the glycogen synthase kinase 3 (GSK3) is an interesting target, since its chemical inhibition activates the Wnt/beta-catenin pathway....

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Detalles Bibliográficos
Autores principales:	Naujok, Ortwin, Lentes, Jana, Diekmann, Ulf, Davenport, Claudia, Lenzen, Sigurd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008422/ https://www.ncbi.nlm.nih.gov/pubmed/24779365 http://dx.doi.org/10.1186/1756-0500-7-273

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