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Is tumor (R)ejection by the immune system the “5th R” of radiobiology?

Traditional factors of DNA damage and tumor cell kill, described by the “4 R’s” of radiobiology (Reassortment, Reoxygenation, Repair, and Repopulation) fall short in explaining the role of immunity in hosts treated with radiotherapy. We propose a “5th R,” (immune-mediated) Rejection, which recognize...

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Detalles Bibliográficos
Autores principales: Golden, Encouse B, Formenti, Silvia C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008452/
https://www.ncbi.nlm.nih.gov/pubmed/24800177
http://dx.doi.org/10.4161/onci.28133

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