Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy

Depending on tumor type, stage and immunological contexture, the inhibition of chemokines or their receptors may yield positive or deleterious effects on disease progression. We have recently demonstrated in several murine models of anthracycline-based chemotherapy that the inhibition of chemokine (...

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Detalles Bibliográficos
Autores principales: Ma, Yuting, Adjemian, Sandy, Galluzzi, Lorenzo, Zitvogel, Laurence, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008453/
https://www.ncbi.nlm.nih.gov/pubmed/24800170
http://dx.doi.org/10.4161/onci.27663
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author Ma, Yuting
Adjemian, Sandy
Galluzzi, Lorenzo
Zitvogel, Laurence
Kroemer, Guido
author_facet Ma, Yuting
Adjemian, Sandy
Galluzzi, Lorenzo
Zitvogel, Laurence
Kroemer, Guido
author_sort Ma, Yuting
collection PubMed
description Depending on tumor type, stage and immunological contexture, the inhibition of chemokines or their receptors may yield positive or deleterious effects on disease progression. We have recently demonstrated in several murine models of anthracycline-based chemotherapy that the inhibition of chemokine (C-C motif) ligand 2 (CCL2) or chemokine (C-C motif) receptor 2 (CCR2) may impair the elicitation of anticancer immune responses that contribute to therapeutic success.
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spelling pubmed-40084532014-05-05 Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy Ma, Yuting Adjemian, Sandy Galluzzi, Lorenzo Zitvogel, Laurence Kroemer, Guido Oncoimmunology Author's View Depending on tumor type, stage and immunological contexture, the inhibition of chemokines or their receptors may yield positive or deleterious effects on disease progression. We have recently demonstrated in several murine models of anthracycline-based chemotherapy that the inhibition of chemokine (C-C motif) ligand 2 (CCL2) or chemokine (C-C motif) receptor 2 (CCR2) may impair the elicitation of anticancer immune responses that contribute to therapeutic success. Landes Bioscience 2014-01-10 /pmc/articles/PMC4008453/ /pubmed/24800170 http://dx.doi.org/10.4161/onci.27663 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Ma, Yuting
Adjemian, Sandy
Galluzzi, Lorenzo
Zitvogel, Laurence
Kroemer, Guido
Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
title Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
title_full Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
title_fullStr Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
title_full_unstemmed Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
title_short Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
title_sort chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008453/
https://www.ncbi.nlm.nih.gov/pubmed/24800170
http://dx.doi.org/10.4161/onci.27663
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AT zitvogellaurence chemokinesandchemokinereceptorsrequiredforoptimalresponsestoanticancerchemotherapy
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