Cargando…

Mitochondrial DNA Variants in Obesity

Heritability estimates for body mass index (BMI) variation are high. For mothers and their offspring higher BMI correlations have been described than for fathers. Variation(s) in the exclusively maternally inherited mitochondrial DNA (mtDNA) might contribute to this parental effect. Thirty-two to 40...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knoll, Nadja, Jarick, Ivonne, Volckmar, Anna-Lena, Klingenspor, Martin, Illig, Thomas, Grallert, Harald, Gieger, Christian, Wichmann, Heinz-Erich, Peters, Annette, Wiegand, Susanna, Biebermann, Heike, Fischer-Posovszky, Pamela, Wabitsch, Martin, Völzke, Henry, Nauck, Matthias, Teumer, Alexander, Rosskopf, Dieter, Rimmbach, Christian, Schreiber, Stefan, Jacobs, Gunnar, Lieb, Wolfgang, Franke, Andre, Hebebrand, Johannes, Hinney, Anke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008486/ https://www.ncbi.nlm.nih.gov/pubmed/24788344 http://dx.doi.org/10.1371/journal.pone.0094882

Ejemplares similares

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants
por: Volckmar, Anna-Lena, et al.
Publicado: (2012)

Gene Set of Nuclear-Encoded Mitochondrial Regulators Is Enriched for Common Inherited Variation in Obesity
por: Knoll, Nadja, et al.
Publicado: (2013)

Investigation of a Genome Wide Association Signal for Obesity: Synthetic Association and Haplotype Analyses at the Melanocortin 4 Receptor Gene Locus
por: Scherag, André, et al.
Publicado: (2010)

Fine Mapping of a GWAS-Derived Obesity Candidate Region on Chromosome 16p11.2
por: Volckmar, Anna-Lena, et al.
Publicado: (2015)

Prevalence estimates of putatively pathogenic leptin variants in the gnomAD database
por: Rajcsanyi, Luisa Sophie, et al.
Publicado: (2022)

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups
por: Vogel, Carla IG, et al.
Publicado: (2009)

Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing
por: Volckmar, Anna-Lena, et al.
Publicado: (2016)

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis
por: Jarick, Ivonne, et al.
Publicado: (2011)

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups
por: Scherag, André, et al.
Publicado: (2010)

A Novel SP1/SP3 Dependent Intronic Enhancer Governing Transcription of the UCP3 Gene in Brown Adipocytes
por: Hoffmann, Christoph, et al.
Publicado: (2013)

Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants
por: Hinney, Anke, et al.
Publicado: (2007)

Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry
por: Vogel, Carla IG, et al.
Publicado: (2009)

Mutation screen and association studies in the Diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13
por: Friedel, Susann, et al.
Publicado: (2007)

Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study
por: Wang, Hai-Jun, et al.
Publicado: (2016)

Increased constraints on MC4R during primate and human evolution
por: Hughes, David A., et al.
Publicado: (2008)

Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity
por: Müller, Timo D, et al.
Publicado: (2010)

Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia
por: Knoll, Susanne, et al.
Publicado: (2008)

Endocrine and Metabolic Effects of Adipose Tissue in Children and Adolescents
por: KOTNIK, Primož, et al.
Publicado: (2015)

Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium
por: Schurmann, Claudia, et al.
Publicado: (2012)

Relevance of polymorphisms in MC4R and BDNF in short normal stature
por: Herrfurth, Nikolas, et al.
Publicado: (2018)

Medical and psychosocial implications of adolescent extreme obesity – acceptance and effects of structured care, short: Youth with Extreme Obesity Study (YES)
por: Wabitsch, Martin, et al.
Publicado: (2013)

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)
por: Tan, Susanne, et al.
Publicado: (2010)

Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1
por: Mühlhaus, Jessica, et al.
Publicado: (2017)

Interleukin-1β Downregulates RBP4 Secretion in Human Adipocytes
por: Kotnik, Primoz, et al.
Publicado: (2013)

Associations between thyroid hormones and serum metabolite profiles in an euthyroid population
por: Jourdan, Carolin, et al.
Publicado: (2013)

Estimated prevalence of potentially damaging variants in the leptin gene
por: Nunziata, Adriana, et al.
Publicado: (2017)

Eating disorders: the current status of molecular genetic research
por: Scherag, Susann, et al.
Publicado: (2009)

Evidence for correlations between BMI-associated SNPs and circRNAs
por: Rajcsanyi, Luisa Sophie, et al.
Publicado: (2022)

The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits
por: Hinney, Anke, et al.
Publicado: (2022)

Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects
por: Milos, Gabriella, et al.
Publicado: (2020)

Prediction of Metabolic Syndrome by Low Serum Testosterone Levels in Men: Results From the Study of Health in Pomerania
por: Haring, Robin, et al.
Publicado: (2009)

THP-1 Macrophages and SGBS Adipocytes – A New Human in vitro Model System of Inflamed Adipose Tissue
por: Keuper, Michaela, et al.
Publicado: (2011)

Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci
por: Ellinghaus, Eva, et al.
Publicado: (2017)

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts
por: Homuth, Georg, et al.
Publicado: (2015)

From monogenic to polygenic obesity: recent advances
por: Hinney, Anke, et al.
Publicado: (2010)

Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder
por: Jarick, I, et al.
Publicado: (2014)

Gender-specific pathway differences in the human serum metabolome
por: Krumsiek, Jan, et al.
Publicado: (2015)

Mapping the Genetic Architecture of Gene Regulation in Whole Blood
por: Schramm, Katharina, et al.
Publicado: (2014)

Comparison of genotyping using pooled DNA samples (allelotyping) and individual genotyping using the affymetrix genome-wide human SNP array 6.0
por: Teumer, Alexander, et al.
Publicado: (2013)

Resveratrol Suppresses PAI-1 Gene Expression in a Human In Vitro Model of Inflamed Adipose Tissue
por: Zagotta, Ivana, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ksslg3444gjc4h2uhohpras51i