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Expression of a Humanized Viral 2A-Mediated lux Operon Efficiently Generates Autonomous Bioluminescence in Human Cells

BACKGROUND: Expression of autonomous bioluminescence from human cells was previously reported to be impossible, suggesting that all bioluminescent-based mammalian reporter systems must therefore require application of a potentially influential chemical substrate. While this was disproven when the ba...

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Detalles Bibliográficos
Autores principales: Xu, Tingting, Ripp, Steven, Sayler, Gary S., Close, Dan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008522/
https://www.ncbi.nlm.nih.gov/pubmed/24788811
http://dx.doi.org/10.1371/journal.pone.0096347