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Filtration Improves the Performance of a High-Throughput Screen for Anti-Mycobacterial Compounds

The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in high-throughput screening (HTS) assays used in the search for novel antibacterial drugs to treat tuberculosis and other related diseases. Here we...

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Detalles Bibliográficos
Autores principales: Cheng, Nancy, Porter, Melissa A., Frick, Lloyd W., Nguyen, Yvonne, Hayden, Jennifer D., Young, Ellen F., Braunstein, Miriam S., Hull-Ryde, Emily A., Janzen, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008622/
https://www.ncbi.nlm.nih.gov/pubmed/24788852
http://dx.doi.org/10.1371/journal.pone.0096348

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