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Filtration Improves the Performance of a High-Throughput Screen for Anti-Mycobacterial Compounds
The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in high-throughput screening (HTS) assays used in the search for novel antibacterial drugs to treat tuberculosis and other related diseases. Here we...
Autores principales: | Cheng, Nancy, Porter, Melissa A., Frick, Lloyd W., Nguyen, Yvonne, Hayden, Jennifer D., Young, Ellen F., Braunstein, Miriam S., Hull-Ryde, Emily A., Janzen, William P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008622/ https://www.ncbi.nlm.nih.gov/pubmed/24788852 http://dx.doi.org/10.1371/journal.pone.0096348 |
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