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Submicron-Bubble-Enhanced Focused Ultrasound for Blood–Brain Barrier Disruption and Improved CNS Drug Delivery
The use of focused ultrasound (FUS) with microbubbles has been proven to induce transient blood–brain barrier opening (BBB-opening). However, FUS-induced inertial cavitation of microbubbles can also result in erythrocyte extravasations. Here we investigated whether induction of submicron bubbles to...
Autores principales: | Fan, Ching-Hsiang, Liu, Hao-Li, Ting, Chien-Yu, Lee, Ya-Hsuan, Huang, Chih-Ying, Ma, Yan-Jung, Wei, Kuo-Chen, Yen, Tzu-Chen, Yeh, Chih-Kuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008627/ https://www.ncbi.nlm.nih.gov/pubmed/24788566 http://dx.doi.org/10.1371/journal.pone.0096327 |
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