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Subfractionation, characterization and in-depth proteomic analysis of glomerular membrane vesicles in human urine
Urinary exosome-like vesicles (ELVs) are a heterogenous mixture (diameter 40–200nm) containing vesicles shed from all segments of the nephron including glomerular podocytes. Contamination with Tamm Horsfall protein (THP) oligomers has hampered their isolation and proteomic analysis. Here we improved...
Autores principales: | Hogan, Marie C., Johnson, Kenneth L., Zenka, Roman M., Charlesworth, M. Cristine, Madden, Benjamin J., Mahoney, Doug W., Oberg, Ann L., Huang, Bing Q., Nesbitt, Lisa L., Bakeberg, Jason L., Bergen, H. Robert, Ward, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008663/ https://www.ncbi.nlm.nih.gov/pubmed/24196483 http://dx.doi.org/10.1038/ki.2013.422 |
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