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Altered coronary artery calcium scores before bariatric surgery
INTRODUCTION: Obesity is an important cause of cardiovascular disease, especially coronary artery disease. Severely obese patients are particularly prone to this risk. The coronary artery calcium (CAC) score is a strong predictor of coronary heart disease and provides incremental information beyond...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008727/ https://www.ncbi.nlm.nih.gov/pubmed/24809002 http://dx.doi.org/10.1186/2193-1801-3-199 |
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author | Gadelha, Patricia S Campos, Josemberg M Moraes, Fernando da F S Leão, Mariana Ferraz, Álvaro A B |
author_facet | Gadelha, Patricia S Campos, Josemberg M Moraes, Fernando da F S Leão, Mariana Ferraz, Álvaro A B |
author_sort | Gadelha, Patricia S |
collection | PubMed |
description | INTRODUCTION: Obesity is an important cause of cardiovascular disease, especially coronary artery disease. Severely obese patients are particularly prone to this risk. The coronary artery calcium (CAC) score is a strong predictor of coronary heart disease and provides incremental information beyond traditional risk factors. We sought to determine the prevalence of abnormally high CAC scores in the preoperative setting among patients undergoing bariatric surgery and to establish risk predictors for higher scores. METHODS: We performed an observational study of 202 patients free of known coronary artery disease who were referred for bariatric surgery. In each patient, the presence of CAC was detected with computed tomography, and coronary risk variables were either measured or determined via questionnaire. RESULTS: CAC was found in 14.4% of the overall population (26% of male and 10.5% of female patients). Participants with altered CAC scores were older (mean age, 46.8 years). The variables positively associated with an altered CAC score were older age, male sex, type 2 diabetes, hypertension, and hypercholesterolemia. Multivariate-adjusted analysis showed that age (OR, 1.11; 95% CI, 1.06–1.17; p = 0.001), male sex (OR, 4.17; 95% CI, 1.52–11.47; p = 0.006), and hypercholesterolemia (OR, 6.21; 95% CI, 1.81–21.29; p = 0.004) were most closely related to the presence of CAC. CONCLUSION: Obese patients in the preoperative bariatric surgery setting have a high prevalence of abnormal CAC scores. Traditional risk factors play a important role in this scenario. |
format | Online Article Text |
id | pubmed-4008727 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-40087272014-05-07 Altered coronary artery calcium scores before bariatric surgery Gadelha, Patricia S Campos, Josemberg M Moraes, Fernando da F S Leão, Mariana Ferraz, Álvaro A B Springerplus Research INTRODUCTION: Obesity is an important cause of cardiovascular disease, especially coronary artery disease. Severely obese patients are particularly prone to this risk. The coronary artery calcium (CAC) score is a strong predictor of coronary heart disease and provides incremental information beyond traditional risk factors. We sought to determine the prevalence of abnormally high CAC scores in the preoperative setting among patients undergoing bariatric surgery and to establish risk predictors for higher scores. METHODS: We performed an observational study of 202 patients free of known coronary artery disease who were referred for bariatric surgery. In each patient, the presence of CAC was detected with computed tomography, and coronary risk variables were either measured or determined via questionnaire. RESULTS: CAC was found in 14.4% of the overall population (26% of male and 10.5% of female patients). Participants with altered CAC scores were older (mean age, 46.8 years). The variables positively associated with an altered CAC score were older age, male sex, type 2 diabetes, hypertension, and hypercholesterolemia. Multivariate-adjusted analysis showed that age (OR, 1.11; 95% CI, 1.06–1.17; p = 0.001), male sex (OR, 4.17; 95% CI, 1.52–11.47; p = 0.006), and hypercholesterolemia (OR, 6.21; 95% CI, 1.81–21.29; p = 0.004) were most closely related to the presence of CAC. CONCLUSION: Obese patients in the preoperative bariatric surgery setting have a high prevalence of abnormal CAC scores. Traditional risk factors play a important role in this scenario. Springer International Publishing 2014-04-22 /pmc/articles/PMC4008727/ /pubmed/24809002 http://dx.doi.org/10.1186/2193-1801-3-199 Text en © Gadelha et al.; licensee Springer. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Research Gadelha, Patricia S Campos, Josemberg M Moraes, Fernando da F S Leão, Mariana Ferraz, Álvaro A B Altered coronary artery calcium scores before bariatric surgery |
title | Altered coronary artery calcium scores before bariatric surgery |
title_full | Altered coronary artery calcium scores before bariatric surgery |
title_fullStr | Altered coronary artery calcium scores before bariatric surgery |
title_full_unstemmed | Altered coronary artery calcium scores before bariatric surgery |
title_short | Altered coronary artery calcium scores before bariatric surgery |
title_sort | altered coronary artery calcium scores before bariatric surgery |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008727/ https://www.ncbi.nlm.nih.gov/pubmed/24809002 http://dx.doi.org/10.1186/2193-1801-3-199 |
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