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Astrocyte Elevated Gene-1 Mediates Glycolysis and Tumorigenesis in Colorectal Carcinoma Cells via AMPK Signaling

To investigate the role of AEG-1 in glycolysis and tumorigenesis, we construct myc-AEG-1 expression vector and demonstrate a novel mechanism that AEG-1 may increase the activity of AMPK by Thr172 phosphorylation. The higher expression levels of AEG-1 in colorectal carcinoma cells were found but show...

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Detalles Bibliográficos
Autores principales:	Song, Hong-tao, Qin, Yu, Yao, Guo-dong, Tian, Zhen-nan, Fu, Song-bin, Geng, Jing-shu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009221/ https://www.ncbi.nlm.nih.gov/pubmed/24829520 http://dx.doi.org/10.1155/2014/287381

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