Exploitation of a Very Small Peptide Nucleic Acid as a New Inhibitor of miR-509-3p Involved in the Regulation of Cystic Fibrosis Disease-Gene Expression

Computational techniques, and in particular molecular dynamics (MD) simulations, have been successfully used as a complementary technique to predict and analyse the structural behaviour of nucleic acids, including peptide nucleic acid- (PNA-) RNA hybrids. This study shows that a 7-base long PNA comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Amato, Felice, Tomaiuolo, Rossella, Nici, Fabrizia, Borbone, Nicola, Elce, Ausilia, Catalanotti, Bruno, D'Errico, Stefano, Morgillo, Carmine Marco, De Rosa, Giuseppe, Mayol, Laura, Piccialli, Gennaro, Oliviero, Giorgia, Castaldo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009323/
https://www.ncbi.nlm.nih.gov/pubmed/24829907
http://dx.doi.org/10.1155/2014/610718

Ejemplares similares

Ejemplares similares