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Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways
Is the order in which proteins assemble into complexes important for biological function? Here, we seek to address this by searching for evidence of evolutionary selection for ordered protein complex assembly. First, we experimentally characterize the assembly pathways of several heteromeric complex...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009401/ https://www.ncbi.nlm.nih.gov/pubmed/23582331 http://dx.doi.org/10.1016/j.cell.2013.02.044 |