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Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways

Is the order in which proteins assemble into complexes important for biological function? Here, we seek to address this by searching for evidence of evolutionary selection for ordered protein complex assembly. First, we experimentally characterize the assembly pathways of several heteromeric complex...

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Detalles Bibliográficos
Autores principales: Marsh, Joseph A., Hernández, Helena, Hall, Zoe, Ahnert, Sebastian E., Perica, Tina, Robinson, Carol V., Teichmann, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009401/
https://www.ncbi.nlm.nih.gov/pubmed/23582331
http://dx.doi.org/10.1016/j.cell.2013.02.044