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Identifying mRNA sequence elements for target recognition by human Argonaute proteins

It is commonly known that mammalian microRNAs (miRNAs) guide the RNA-induced silencing complex (RISC) to target mRNAs through the seed-pairing rule. However, recent experiments that coimmunoprecipitate the Argonaute proteins (AGOs), the central catalytic component of RISC, have consistently revealed...

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Detalles Bibliográficos
Autores principales:	Li, Jingjing, Kim, TaeHyung, Nutiu, Razvan, Ray, Debashish, Hughes, Timothy R., Zhang, Zhaolei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009607/ https://www.ncbi.nlm.nih.gov/pubmed/24663241 http://dx.doi.org/10.1101/gr.162230.113

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