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High-resolution mapping defines the cooperative architecture of Polycomb response elements

Polycomb-mediated chromatin repression modulates gene expression during development in metazoans. Binding of multiple sequence-specific factors at discrete Polycomb response elements (PREs) is thought to recruit repressive complexes that spread across an extended chromatin domain. To dissect the str...

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Detalles Bibliográficos
Autores principales: Orsi, Guillermo A., Kasinathan, Sivakanthan, Hughes, Kelly T., Saminadin-Peter, Sarah, Henikoff, Steven, Ahmad, Kami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009610/
https://www.ncbi.nlm.nih.gov/pubmed/24668908
http://dx.doi.org/10.1101/gr.163642.113