Miniaturized Bioaffinity Assessment Coupled to Mass Spectrometry for Guided Purification of Bioactives from Toad and Cone Snail

A nano-flow high-resolution screening platform, featuring a parallel chip-based microfluidic bioassay and mass spectrometry coupled to nano-liquid chromatography, was applied to screen animal venoms for nicotinic acetylcholine receptor like (nAChR) affinity by using the acetylcholine binding protein...

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Detalles Bibliográficos
Autores principales: Heus, Ferry, Otvos, Reka A., Aspers, Ruud L. E. G., van Elk, Rene, Halff, Jenny I., Ehlers, Andreas W., Dutertre, Sébastien, Lewis, Richard J., Wijmenga, Sybren, Smit, August B., Niessen, Wilfried M. A., Kool, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009767/
https://www.ncbi.nlm.nih.gov/pubmed/24833338
http://dx.doi.org/10.3390/biology3010139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009767/
https://www.ncbi.nlm.nih.gov/pubmed/24833338
http://dx.doi.org/10.3390/biology3010139

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