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Free Energy Profile of APOBEC3G Protein Calculated by a Molecular Dynamics Simulation

The human APOBEC3G protein (A3G) is a single-stranded DNA deaminase that inhibits the replication of retrotransposons and retroviruses, including HIV-1. Atomic details of A3G’s catalytic mechanism have started to emerge, as the structure of its catalytic domain (A3Gctd) has been revealed by NMR and...

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Detalles Bibliográficos
Autores principales:	Fukunishi, Yoshifumi, Hongo, Saki, Lintuluoto, Masami, Matsuo, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009775/ https://www.ncbi.nlm.nih.gov/pubmed/24832225 http://dx.doi.org/10.3390/biology1020245

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