HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods

The binding between the HIV-1 trans-activator of transcription (Tat) and p300/(CREB-binding protein)-associated factor (PCAF) bromodomain is a crucial step in the HIV-1 life cycle. However, the structure of the full length acetylated Tat bound to PCAF has not been yet determined experimentally. Acet...

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Detalles Bibliográficos
Autores principales: Quy, Vo Cam, Pantano, Sergio, Rossetti, Giulia, Giacca, Mauro, Carloni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009784/
https://www.ncbi.nlm.nih.gov/pubmed/24832227
http://dx.doi.org/10.3390/biology1020277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009784/
https://www.ncbi.nlm.nih.gov/pubmed/24832227
http://dx.doi.org/10.3390/biology1020277

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