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Understanding the Dynamics of Gene Regulatory Systems; Characterisation and Clinical Relevance of cis-Regulatory Polymorphisms

Modern genetic analysis has shown that most polymorphisms associated with human disease are non-coding. Much of the functional information contained in the non-coding genome consists of cis-regulatory sequences (CRSs) that are required to respond to signal transduction cues that direct cell specific...

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Detalles Bibliográficos
Autores principales:	Cowie, Philip, Ross, Ruth, MacKenzie, Alasdair
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009875/ https://www.ncbi.nlm.nih.gov/pubmed/24832652 http://dx.doi.org/10.3390/biology2010064

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