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Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke

Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be success...

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Detalles Bibliográficos
Autores principales: Jin, Qi, Chen, Erzhen, Jiang, Jie, Lu, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010014/
https://www.ncbi.nlm.nih.gov/pubmed/24826335
http://dx.doi.org/10.1155/2012/295867
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author Jin, Qi
Chen, Erzhen
Jiang, Jie
Lu, Yiming
author_facet Jin, Qi
Chen, Erzhen
Jiang, Jie
Lu, Yiming
author_sort Jin, Qi
collection PubMed
description Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS.
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spelling pubmed-40100142014-05-13 Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke Jin, Qi Chen, Erzhen Jiang, Jie Lu, Yiming Case Rep Crit Care Case Report Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS. Hindawi Publishing Corporation 2012 2012-06-28 /pmc/articles/PMC4010014/ /pubmed/24826335 http://dx.doi.org/10.1155/2012/295867 Text en Copyright © 2012 Qi Jin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jin, Qi
Chen, Erzhen
Jiang, Jie
Lu, Yiming
Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_full Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_fullStr Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_full_unstemmed Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_short Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
title_sort acute hepatic failure as a leading manifestation in exertional heat stroke
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010014/
https://www.ncbi.nlm.nih.gov/pubmed/24826335
http://dx.doi.org/10.1155/2012/295867
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