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Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke
Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be success...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010014/ https://www.ncbi.nlm.nih.gov/pubmed/24826335 http://dx.doi.org/10.1155/2012/295867 |
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author | Jin, Qi Chen, Erzhen Jiang, Jie Lu, Yiming |
author_facet | Jin, Qi Chen, Erzhen Jiang, Jie Lu, Yiming |
author_sort | Jin, Qi |
collection | PubMed |
description | Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS. |
format | Online Article Text |
id | pubmed-4010014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-40100142014-05-13 Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke Jin, Qi Chen, Erzhen Jiang, Jie Lu, Yiming Case Rep Crit Care Case Report Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation. Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors. Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS. Hindawi Publishing Corporation 2012 2012-06-28 /pmc/articles/PMC4010014/ /pubmed/24826335 http://dx.doi.org/10.1155/2012/295867 Text en Copyright © 2012 Qi Jin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Jin, Qi Chen, Erzhen Jiang, Jie Lu, Yiming Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_full | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_fullStr | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_full_unstemmed | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_short | Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke |
title_sort | acute hepatic failure as a leading manifestation in exertional heat stroke |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010014/ https://www.ncbi.nlm.nih.gov/pubmed/24826335 http://dx.doi.org/10.1155/2012/295867 |
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