Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus

Nurofen Plus is a common analgesic containing ibuprofen and codeine. We present a case of a 38-year-old lady who developed renal tubular acidosis with severe hypokalaemia, after chronic abuse of Nurofen Plus tablets. She presented with confusion and profound biochemical abnormalities requiring criti...

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Detalles Bibliográficos
Autores principales: Blackstock, M. J., Lee, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010031/
https://www.ncbi.nlm.nih.gov/pubmed/24826329
http://dx.doi.org/10.1155/2012/141505
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author Blackstock, M. J.
Lee, A.
author_facet Blackstock, M. J.
Lee, A.
author_sort Blackstock, M. J.
collection PubMed
description Nurofen Plus is a common analgesic containing ibuprofen and codeine. We present a case of a 38-year-old lady who developed renal tubular acidosis with severe hypokalaemia, after chronic abuse of Nurofen Plus tablets. She presented with confusion and profound biochemical abnormalities requiring critical care admission for electrolyte replacement. Ibuprofen causes renal tubular acidosis due to its effects on carbonic anhydrase activity.
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spelling pubmed-40100312014-05-13 Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus Blackstock, M. J. Lee, A. Case Rep Crit Care Case Report Nurofen Plus is a common analgesic containing ibuprofen and codeine. We present a case of a 38-year-old lady who developed renal tubular acidosis with severe hypokalaemia, after chronic abuse of Nurofen Plus tablets. She presented with confusion and profound biochemical abnormalities requiring critical care admission for electrolyte replacement. Ibuprofen causes renal tubular acidosis due to its effects on carbonic anhydrase activity. Hindawi Publishing Corporation 2012 2012-08-29 /pmc/articles/PMC4010031/ /pubmed/24826329 http://dx.doi.org/10.1155/2012/141505 Text en Copyright © 2012 M. J. Blackstock and A. Lee. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Blackstock, M. J.
Lee, A.
Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus
title Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus
title_full Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus
title_fullStr Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus
title_full_unstemmed Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus
title_short Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus
title_sort hypokalaemia and renal tubular acidosis due to abuse of nurofen plus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010031/
https://www.ncbi.nlm.nih.gov/pubmed/24826329
http://dx.doi.org/10.1155/2012/141505
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