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Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia

Hyoscine N-butyl bromide, also known as scopolamine, is a type of antimuscarinic agent. This drug is associated with numerous common side effects, including abdominal fullness, constipation, urinary retention, blurred vision, skin flushing, tachycardia, decreased sweating, and salivation. The most u...

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Autores principales: Chen, Guan-Liang, Hsu, Wen-Hsiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010047/
https://www.ncbi.nlm.nih.gov/pubmed/24829823
http://dx.doi.org/10.1155/2013/414856
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author Chen, Guan-Liang
Hsu, Wen-Hsiu
author_facet Chen, Guan-Liang
Hsu, Wen-Hsiu
author_sort Chen, Guan-Liang
collection PubMed
description Hyoscine N-butyl bromide, also known as scopolamine, is a type of antimuscarinic agent. This drug is associated with numerous common side effects, including abdominal fullness, constipation, urinary retention, blurred vision, skin flushing, tachycardia, decreased sweating, and salivation. The most unfavorable side effect is hemodynamic instability. In the present case, hypotension and acute myocardial infarction developed after intravenous hyoscine injection as a premedication therapy for colonoscopy. It was difficult to differentiate the cause-effect relationship between myocardial infarction and hypotension. Because both conditions were present under drug effects, we considered 2 possible diagnoses. One was coronary spasm with cardiogenic shock, and the other was myocardial ischemic sequela due to shock status. The latter diagnosis was confirmed after a series of examinations.
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spelling pubmed-40100472014-05-14 Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia Chen, Guan-Liang Hsu, Wen-Hsiu Case Rep Crit Care Case Report Hyoscine N-butyl bromide, also known as scopolamine, is a type of antimuscarinic agent. This drug is associated with numerous common side effects, including abdominal fullness, constipation, urinary retention, blurred vision, skin flushing, tachycardia, decreased sweating, and salivation. The most unfavorable side effect is hemodynamic instability. In the present case, hypotension and acute myocardial infarction developed after intravenous hyoscine injection as a premedication therapy for colonoscopy. It was difficult to differentiate the cause-effect relationship between myocardial infarction and hypotension. Because both conditions were present under drug effects, we considered 2 possible diagnoses. One was coronary spasm with cardiogenic shock, and the other was myocardial ischemic sequela due to shock status. The latter diagnosis was confirmed after a series of examinations. Hindawi Publishing Corporation 2013 2013-01-28 /pmc/articles/PMC4010047/ /pubmed/24829823 http://dx.doi.org/10.1155/2013/414856 Text en Copyright © 2013 G.-L. Chen and W.-H. Hsu. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chen, Guan-Liang
Hsu, Wen-Hsiu
Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia
title Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia
title_full Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia
title_fullStr Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia
title_full_unstemmed Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia
title_short Hyoscine-N-Butyl-Bromide-Induced Hypotension and Myocardial Ischemia
title_sort hyoscine-n-butyl-bromide-induced hypotension and myocardial ischemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010047/
https://www.ncbi.nlm.nih.gov/pubmed/24829823
http://dx.doi.org/10.1155/2013/414856
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