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Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1

[Image: see text] The myosin light chain phosphatase (MLCP) is a cytoskeleton-associated protein phosphatase-1 (PP1) holoenzyme and a RhoA/ROCK effector, regulating cytoskeletal reorganization. ROCK-induced phosphorylation of the MLCP regulatory subunit (MYPT1) at two sites, Thr696 and Thr853, suppr...

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Detalles Bibliográficos
Autores principales:	Khasnis, Mukta, Nakatomi, Akiko, Gumpper, Kristyn, Eto, Masumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010256/ https://www.ncbi.nlm.nih.gov/pubmed/24712327 http://dx.doi.org/10.1021/bi5001728

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