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Continuing a Cancer Treatment Despite Tumor Growth May Be Valuable: Sunitinib in Renal Cell Carcinoma as Example
BACKGROUND: The US FDA and the EMA have approved seven agents for the treatment of renal cell carcinoma, primarily based on differences in progression-free survival (PFS). Because PFS is an arbitrary endpoint we hypothesized that an analysis would demonstrate the growth rate of tumors remained const...
Autores principales: | Burotto, Mauricio, Wilkerson, Julia, Stein, Wilfred, Motzer, Robert, Bates, Susan, Fojo, Tito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010463/ https://www.ncbi.nlm.nih.gov/pubmed/24796484 http://dx.doi.org/10.1371/journal.pone.0096316 |
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