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Harnessing High Density Lipoproteins to Block Transforming Growth Factor Beta and to Inhibit the Growth of Liver Tumor Metastases
Transforming growth factor β (TGF-β) is a powerful promoter of cancer progression and a key target for antitumor therapy. As cancer cells exhibit active cholesterol metabolism, high density lipoproteins (HDLs) appear as an attractive delivery system for anticancer TGFβ-inhibitory molecules. We const...
Autores principales: | Medina-Echeverz, José, Fioravanti, Jessica, Díaz-Valdés, Nancy, Frank, Kathrin, Aranda, Fernando, Gomar, Celia, Ardaiz, Nuria, Dotor, Javier, Umansky, Viktor, Prieto, Jesús, Berraondo, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010484/ https://www.ncbi.nlm.nih.gov/pubmed/24797128 http://dx.doi.org/10.1371/journal.pone.0096799 |
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