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Apamin Does Not Inhibit Human Cardiac Na(+) Current, L-type Ca(2+) Current or Other Major K(+) Currents
BACKGROUND: Apamin is commonly used as a small-conductance Ca(2+)-activated K(+) (SK) current inhibitor. However, the specificity of apamin in cardiac tissues remains unclear. OBJECTIVE: To test the hypothesis that apamin does not inhibit any major cardiac ion currents. METHODS: We studied human emb...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010514/ https://www.ncbi.nlm.nih.gov/pubmed/24798465 http://dx.doi.org/10.1371/journal.pone.0096691 |