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The Immunosuppressant Protosappanin A Diminished Recipient T Cell Migration into Allograft via Inhibition of IP-10 in Rat Heart Transplant

The immunosuppressant Protosappanin A (PrA), isolated from the medicinal herb, promotes cardiac allograft survival, diminishes inflammatory cell infiltration, and inhibits interferon γ-induced protein 10 kDa (IP-10) mRNA expression in rats cardiac grafts. Binding of the chemokine IP-10 to its cognat...

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Detalles Bibliográficos
Autores principales: Zhang, Maomao, He, Jieqiong, Hou, Jingbo, Wu, Jian, Sun, Meng, Cui, Jinjin, Tian, Jiangtian, Jiang, Miaomiao, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010525/
https://www.ncbi.nlm.nih.gov/pubmed/24798458
http://dx.doi.org/10.1371/journal.pone.0096138

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