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Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats
Vaccination against the highly abused prescription opioid oxycodone has shown pre-clinical efficacy for blocking oxycodone effects. The current study further evaluated a candidate vaccine composed of oxycodone derivatized at the C6 position (6OXY) conjugated to the native keyhole limpet hemocyanin (...
Autores principales: | Pravetoni, Marco, Vervacke, Jeffrey S., Distefano, Mark D., Tucker, Ashli M., Laudenbach, Megan, Pentel, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010527/ https://www.ncbi.nlm.nih.gov/pubmed/24797666 http://dx.doi.org/10.1371/journal.pone.0096547 |
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