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Poldip2 Knockout Results in Perinatal Lethality, Reduced Cellular Growth and Increased Autophagy of Mouse Embryonic Fibroblasts

Polymerase-δ interacting protein 2 (Poldip2) is an understudied protein, originally described as a binding partner of polymerase delta and proliferating cell nuclear antigen (PCNA). Numerous roles for Poldip2 have been proposed, including mitochondrial elongation, DNA replication/repair and ROS prod...

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Detalles Bibliográficos
Autores principales: Brown, David I., Lassègue, Bernard, Lee, Minyoung, Zafari, Rostam, Long, James S., Saavedra, Harold I., Griendling, Kathy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010529/
https://www.ncbi.nlm.nih.gov/pubmed/24797518
http://dx.doi.org/10.1371/journal.pone.0096657

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