Cargando…
Poldip2 Knockout Results in Perinatal Lethality, Reduced Cellular Growth and Increased Autophagy of Mouse Embryonic Fibroblasts
Polymerase-δ interacting protein 2 (Poldip2) is an understudied protein, originally described as a binding partner of polymerase delta and proliferating cell nuclear antigen (PCNA). Numerous roles for Poldip2 have been proposed, including mitochondrial elongation, DNA replication/repair and ROS prod...
Autores principales: | Brown, David I., Lassègue, Bernard, Lee, Minyoung, Zafari, Rostam, Long, James S., Saavedra, Harold I., Griendling, Kathy K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010529/ https://www.ncbi.nlm.nih.gov/pubmed/24797518 http://dx.doi.org/10.1371/journal.pone.0096657 |
Ejemplares similares
-
Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting
por: Lassègue, Bernard, et al.
Publicado: (2021) -
Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
por: Kikuchi, Daniel S., et al.
Publicado: (2019) -
Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome
por: Ou, Ziwei, et al.
Publicado: (2022) -
Poldip2 Knockdown Inhibits Vascular Smooth Muscle Proliferation and Neointima Formation by Regulating the Expression of PCNA and p21
por: Datla, Srinivasa Raju, et al.
Publicado: (2018) -
Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer
por: Paredes, Felipe, et al.
Publicado: (2018)