Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

Bladder cancers are a leading cause of death from malignancy. Molecular markers might predict disease progression and behaviour more accurately than the available prognostic factors. Here we use whole-genome sequencing to identify somatic mutations and chromosomal changes in 14 bladder cancers of di...

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Detalles Bibliográficos
Autores principales: Cazier, J.-B., Rao, S.R., McLean, C.M., Walker, A.L., Wright, B.J., Jaeger, E.E.M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J.W., Tomlinson, I.P.M., Kiltie, A.E., Hamdy, F.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010643/
https://www.ncbi.nlm.nih.gov/pubmed/24777035
http://dx.doi.org/10.1038/ncomms4756

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